GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs4815421 | chr20:25386509 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000546 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815421 | chr20:25386509 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.05E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815421 | chr20:25386509 | NINL | chr20:25433338-25566153:- | 0.33 | 6.9 | 1.67E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815421 | chr20:25386509 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.53E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815424 | chr20:25390284 | ENTPD6 | chr20:25176339-25207360:+ | 0.3 | 6.64 | 8.57E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815424 | chr20:25390284 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.43 | 9.22E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815424 | chr20:25390284 | NINL | chr20:25433338-25566153:- | 0.35 | 7.14 | 3.59E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815424 | chr20:25390284 | PYGB | chr20:25228706-25278647:+ | 0.14 | 3.5 | 0.000507 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815426 | chr20:25405186 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.43 | 5.2E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815426 | chr20:25405186 | FAM182A | chr20:26035250-26067552:+ | 0.18 | 3.44 | 0.000637 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815426 | chr20:25405186 | FAM182B | chr20:25744102-25848786:- | -0.25 | -5.26 | 2.22E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815426 | chr20:25405186 | NINL | chr20:25433338-25566153:- | 0.34 | 7.1 | 4.42E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4815426 | chr20:25405186 | PYGB | chr20:25228706-25278647:+ | 0.15 | 3.79 | 0.000167 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs4819388 | 1 | rs4819388 | chr21:45647421 | ICOSLG | chr21:45646724-45660834:- | -0.23 | -4.71 | 3.25E-6 | Celiac disease |
| THCA | cis | rs4141404 | 1 | rs4820043 | chr22:31647094 | RNF185 | chr22:31556138-31603004:+ | -0.28 | -5.18 | 3.21E-7 | Paclitaxel-induced neuropathy |